As is the case with the films in the Alien franchise, the game is going to be set in space.
New Aliens Game Has Been Announced
Submitted by WindowsNexus
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Gangsta_Red
I don't know why but I think an isometric gameplay Alien game set on a huge abandoned space freighter type ship would be terrifying. No music, just the constant noise of the ship slowly degrading in some orbit over a dead planet.
WindowsNexus
It needs a lot of work but yeah I can see it done very well.